产品货号：
Z26135
中文名称：
SELK抗体
英文名称：
Anti-SELK Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SELK Antibody |
| 指标别名 | HSPC030,HSPC297,selenoprotein K,SELK |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IF |
| 基因名称 | SELK |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | SELK antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SELK.The immunogen is located within the last 50 amino acids of SELK. |
| 计算分子量 | 11kDa |
| 成分 | SELK Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | SELK Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | SELK is a selenoprotein,containing a selenocysteine residue at its active site.SELK is localized to the endoplasmic reticulum and is highly expressed in the heart,where it may function as an antioxidant.SELK can bind to proteins such as the ER-associated degradation (ERAD) components p97 ATPase,Derlin-1 and -2,and SelS as well as proteins in the oligosaccharyltransferase complex,suggesting that SELK may be involved in the Derlin-dependent ERAD of glycosylated misfolded proteins.SELK is also thought to be important in Ca2+ flux in immune cells,and is cleaved by m-calpain in resting macrophages.When these macrophages are activated through different Toll-like receptors,this cleavage is inhibited |
| Uniprot ID | Q9Y6D0 |
| 基因名全称 | Selenoprotein K |
| 蛋白名全称 | Selenoprotein K |
| 推荐稀释比 | SELK antibody can be used for detection of SELK by Western blot at 1 ～ 2μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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